

SYNTHESIS OF FERROCENE-BASED POLYSUBSTITUTED PYRROLIDINES

Abstract
Ferrocene-based polysubstituted pyrrolidines can be synthesized efficiently via 1,3-dipolar cycloaddition of azomethine ylides generated from α-amino acid ester and ferrocenecarboxaldehyde with N-substituted maleimide at 125°C in MeCN. The structures of the products were confirmed by 1H, 13C NMR, and HRMS data.
Keywords
azomethine ylides; ferrocene; pyrrolidine; 1,3-dipolar cycloaddition.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv