

FLUORINE-CONTAINING FURAN-3(2Н)-ONES IN REACTIONS WITH BINUCLEOPHILES: CF3 vs C2F5

Abstract
Five- and six-membered fluorine-containing azaheterocycles were synthesized based on available furan-3(2H)-ones, and the influence of the nature of the fluoroalkyl substituent on the direction of the chemical transformations by the action of N,N- and N,O-binucleophiles was revealed.
Keywords
4,7-dihydro[1,2,4]triazolo[1,5-а]pyrimidine; furan-3(2Н)-ones; 2-methoxy-2-methyl-5-(perfluoroethyl)furan-3(2Н)-one; pyrazole; 1,1,1-trifluoro-3-(2-methylpyrido[2,3-b]pyrazin-3(4Н)-ylidene)propan-2-one; N,N- and N,O-binucleophiles
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv