THREE-COMPONENT CONDENSATION OF 4-IMINO-1-PHENYLIMIDAZOLIDIN-2-ONE WITH ALDEHYDES AND MELDRUM'S ACID: SYNTHESIS OF IMIDAZO[4,5-<i>b</i>]PYRIDINE-2,5(4<i>H</i>,6<i>H</i>)-DIONES AND 5-SUBSTITUTED 1-PHENYLHYDANTOINS
Authors
Константин С. Крылов
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
Андрей Н. Комогорцев
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
Борис В. Личицкий
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
Артем Н. Фахрутдинов
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
Аркадий А. Дудинов
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
Михаил М. Краюшкин
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
A convenient method for the synthesis of previously unknown imidazo[4,5-b]pyridine-2,5(4H,6H)-diones has been developed, based on a three-component condensation of 4-imino-1-phenylimidazolidin-2-one with aldehydes and Meldrum's acid. The possibility of accessing 5-substituted 1-phenylhydantoins based on the acid hydrolysis of imidazo[4,5-b]pyridine-2,5(4H,6H)-diones was shown.
