Open Access Open Access  Restricted Access Subscription Access

FLUORINATED 1,3-BENZOTHIAZIN-4-ONES CONTAINING FLUOROQUINOLONE FRAGMENT

Emiliya V. Nosova, Olga A. Batanova, Nataliya N. Mochulskaya, Valery N. Charushin
Cover Image

Abstract


We have developed an efficient synthetic approach to potential antibacterial agents with double mechanism of action through the combination of antibacterial fluoroquinolones with 1,3-benzothiazin-4-ones.

Keywords


fluorobenzothiazin-4-ones; o-fluorobenzoyl isothiocyanates; 7-hydrazinoquinolone-3-carboxylic acid; quinolone-3-carboxylic acid hydrazides; cyclocondensation

Full Text: PDF Supplementary File(s): None


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv