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EFFICIENT ONE-STEP SYNTHESIS OF 3-ARYL-2-PYRIDONES FROM 6-ARYL-1,2,4-TRIAZIN-5-ONES

Мария И. Савчук, Ярослав К. Штайц, Дмитрий С. Копчук, Григорий В. Зырянов, Олег С. Ельцов, Татьяна А. Поспелова, Владимир Л. Русинов, Олег Н. Чупахин
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Abstract


An efficient method for the synthesis of substituted 2-pyridones based on the aza-Diels–Alder reaction of 1,2,4-triazin-5-ones and dienophiles, 2,5-norbornadiene and 4-(cyclopent-1-en-1-yl)morpholine, is proposed.

Keywords


2,2'-bipyridine; 2-pyridone; 1,2,4-triazin-5-one; autoclave; aza-Diels–Alder reaction; nucleophilic ipso-substitution.

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