SYNTHESIS OF QUINAZOLIN-4(3<i>H</i>)-ONES <i>via</i> THE REACTION OF ISATOIC ANHYDRIDE WITH BENZYL AZIDES IN THE PRESENCE OF POTASSIUM <i>tert</i>-BUTOXIDE IN DMSO

Authors

  • Mohammad H. Sayahi Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran
  • Saeed Bahadorikhalili School of Chemistry, College of Science, University of Tehran, Tehran
  • Mohammad Mahdavi Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran
  • Laleh Baghshirin Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran

DOI:

https://doi.org/10.1007/5123

Keywords:

benzyl azides, isatoic anhydride, potassium tert-butoxide, quinazolin-4(3H)-ones

Abstract

In this paper, a novel method is described for the synthesis of 4(3H)-quinazolinone derivatives via the reaction of isatoic anhydride with benzyl azides in the presence of potassium tert-butoxide in DMSO. The reaction is completed after 4 h at 100 °C to produce the titled products in good yields.

Author Biography

Saeed Bahadorikhalili, School of Chemistry, College of Science, University of Tehran, Tehran

s.bahadorikhalili@isrc.ac.ir

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Published

2019-09-26

Issue

Vol. 55 No. 10 (2019)

Section

Original Papers