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SYNTHESIS OF QUINAZOLIN-4(3H)-ONES via THE REACTION OF ISATOIC ANHYDRIDE WITH BENZYL AZIDES IN THE PRESENCE OF POTASSIUM tert-BUTOXIDE IN DMSO

Mohammad H. Sayahi, Saeed Bahadorikhalili, Mohammad Mahdavi, Laleh Baghshirin
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Abstract


In this paper, a novel method is described for the synthesis of 4(3H)-quinazolinone derivatives via the reaction of isatoic anhydride with benzyl azides in the presence of potassium tert-butoxide in DMSO. The reaction is completed after 4 h at 100 °C to produce the titled products in good yields.


Keywords


benzyl azides; isatoic anhydride; potassium tert-butoxide; quinazolin-4(3H)-ones

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