

SYNTHESIS OF NOVEL N,O-MACROCYCLIC LIGANDS, FUNCTIONALIZED BY PHOSPHINE OXIDE GROUPS

Abstract
As a result of the implementation of two approaches, the Pudovik reaction (the reaction of macrocyclic azomethines with secondary phosphine oxides) and the Kabachnik–Fields reaction (three-component one-pot process involving dialdehydes, diamines, and secondary phosphine oxides), novel N,O-containing macrocyclic ligands with phosphine oxide groups were first obtained. The synthesized macrocycles are a kind of α-aminophosphoryl compounds that can be used in the synthesis of supramolecular systems.
Keywords
α-aminophosphoryl compounds; N,O-macrocyclic ligands; Kabachnik–Fields reaction; Pudovik reaction.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv