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A SIMPLE METHOD FOR THE SYNTHESIS OF PYRAZOLO[1,5-d][1,2,4]TRIAZINES via THE REACTION OF TETRACARBONYL COMPOUNDS WITH THIOCARBONOHYDRAZIDE

Александр И. Кобелев, Екатерина Е. Степанова, Максим В. Дмитриев, Андрей Н. Масливец
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Abstract


1,3,4,6-Tetracarbonyl compounds undergo a series of cascade condensations with thiocarbonohydrazide to form substituted pyrazolo[1,5-d][1,2,4]triazines. The studied transformations proceed in good yields under catalyst-free conditions, and the reaction products are isolated without the use of column chromatography.

Keywords


aza-heterocycle, pyrazolo[1,5-d][1,2,4]triazine, tetracarbonyl compounds, thiocarbonohydrazide, condensation

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv