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ONE-POT SYNTHESIS OF QUATERNARY PYRIDINIUM SALTS AND TETRAHYDROPYRIDINE DERIVATIVES OF FUSIDANE TRITERPENOIDS

Эльвира Р. Шакурова, Елена В. Салимова, Екатерина С. Мещерякова, Людмила В. Парфёнова
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Abstract


An efficient one-pot method was developed for the preparation of quaternary pyridinium salts and tetrahydropyridine derivatives of fusidane triterpenoids, based on the use of Tempo+Br3 – as the halogenating agent and pyridine as the reagent and solvent.

Keywords


fusidic acid; quaternary pyridinium salts; Tempo+Br3 –; antimicrobial activity.

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