ONE-POT SYNTHESIS OF QUATERNARY PYRIDINIUM SALTS AND TETRAHYDROPYRIDINE DERIVATIVES OF FUSIDANE TRITERPENOIDS
Authors
Эльвира Р. Шакурова
Institute of Petrochemistry and Catalysis,
Ufa Federal Research Center of the Russian Academy of Sciences,
141 Oktyabrya Ave., Ufa 450075, Russia
Елена В. Салимова
Institute of Petrochemistry and Catalysis,
Ufa Federal Research Center of the Russian Academy of Sciences,
141 Oktyabrya Ave., Ufa 450075, Russia
Екатерина С. Мещерякова
Institute of Petrochemistry and Catalysis,
Ufa Federal Research Center of the Russian Academy of Sciences,
141 Oktyabrya Ave., Ufa 450075, Russia
Людмила В. Парфёнова
Institute of Petrochemistry and Catalysis,
Ufa Federal Research Center of the Russian Academy of Sciences,
141 Oktyabrya Ave., Ufa 450075, Russia
fusidic acid, quaternary pyridinium salts, Tempo Br3 –, antimicrobial activity.
Abstract
An efficient one-pot method was developed for the preparation of quaternary pyridinium salts and tetrahydropyridine derivatives of fusidane triterpenoids, based on the use of Tempo+Br3 – as the halogenating agent and pyridine as the reagent and solvent.
