REACTION OF 1,2,3,4-TETRAHYDRO-2,4,5-TRIMETHYLPYRROLO[1,2-<i>c</i>]PYRIMIDINE AND ITS 7-FORMYL-SUBSTITUTED DERIVATIVE WITH NITRIC ACID

Authors

  • А. B. Варламов Russian University of International Friendship
  • T. H. Борисова Russian University of International Friendship
  • E. А. Сорокина Russian University of International Friendship
  • А. И. Чернышев Russian University of International Friendship

DOI:

https://doi.org/10.1007/532

Abstract

1,2,3,4-Tetrahydro-2,4,5-trimethylpyrrolo[1,2-c]pyrimidine and its 7-formyl derivative when treated with nitric acid are converted to substituted tetrahydropyrrolo-[1,2-c]pyrimidine-7-carboxylic acid. Conversion occurs through opening of the aminal moiety and formylation of the second molecule of tetrahydropyrrolo[1,2-c]pyrimidine by formaldehyde formed to the 7-formyl-substituted derivative.

Authors: A. V. Varlamov, T. N. Borisova, E. A. Sorokina, and A. I. Chernyshev.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (2), pp 195-198

http://link.springer.com/article/10.1007/BF02251708

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Published

2013-04-26

Issue

No. 2 (1999)

Section

Original Papers