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THE PRODUCTS OF SUZUKI REACTION OF ETHYL 4-CHLORO-5-METHYLTHIENO[2,3-d]PYRIMIDINE-6-CARBOXYLATE WITH POTASSIUM ALLYLTRIFLUOROBORATE AND TRANSFORMATIONS THEREOF

Konstantin Yu. Krolenko, Sergiy V. Vlasov
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Abstract


5-Methylthieno[2,3-d]pyrimidine-6-carboxylates substituted with prop-1-en-1-yl and hexa-1,5-dien-3-yl fragments in the C-4 position of the heterocycle were obtained in Suzuki coupling reaction of potassium allyltrifluoroborate and ethyl 4-chloro-5-methylthieno[2,3-d]pyrimidine-6-carboxylate. Further transformations of the products allowed confirming the structure and molecular geometry of the obtained compounds.

Keywords


hexa-1,5-dien-3-yl derivatives; potassium allyltrifluoroborate; thieno[2,3-d]pyrimidine; Cope rearrangement; Suzuki reaction

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv