ALIPHATIC ALDEHYDES IN SYNTHESIS OF 4-ALKYL-5-CARBAMOYL-3-CYANO-6-METHYLPYRIDINE-2(1H)-THIONES

Authors

  • С. Г. Кривоколыско Lugansk T. G. Shevchenko State Pedagogical Institute
  • B. Д. Дяченко Lugansk T. G. Shevchenko State Pedagogical Institute
  • B. П. Литвинов N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/534

Abstract

Condensation of isovaleric or acetic aldehydes with cyanothioacetamide and acetoacetamide leads to formation of 4-isobutyl(methyl)-5-carbamoyl-3-cyano-6-methylpyridine-2(1H)-thiones. By alkylation of 5-carbamoyl-3-cyano-4,6-dimethylpyridine-2(1H)-thione with 4-methoxyphenacyl bromide, 5-carbamoyl-3-cyano-4,6-dimethyl-2-(4-methoxybenzoyl)methylthiopyridine has been obtained.

Authors: S. G. Krivokolysko, V. D. Dyachenko, and V. P. Litvinov.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (2), pp 204-205

http://link.springer.com/article/10.1007/BF02251710

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Published

2013-04-29

Issue

No. 2 (1999)

Section

Original Papers