

HETARYL-SUBSTITUTED BICYCLO[1.1.1]PENTANES

Abstract
Synthesis and properties of heterocycles bearing bicyclo[1.1.1]pentane moiety attached to the heterocyclic ring are summarized in this microreview. In particular, heterocyclizations with bicyclo[1.1.1]pentane derivatives, as well as reactions involving incorporation of the preexisting heterocyclic system into the bicyclo[1.1.1]pentane core are discussed.
Keywords
Nitrogen heterocycles; Isosteres; Heterocyclization; Palladium-catalyzed couplings; Radical reactions
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv