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HETARYL-SUBSTITUTED BICYCLO[1.1.1]PENTANES

Oleksandr O. Grygorenko, Serhii O. Kokhan
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Abstract


Synthesis and properties of heterocycles bearing bicyclo[1.1.1]pentane moiety attached to the heterocyclic ring are summarized in this microreview. In particular, heterocyclizations with bicyclo[1.1.1]pentane derivatives, as well as reactions involving incorporation of the preexisting heterocyclic system into the bicyclo[1.1.1]pentane core are discussed.

Keywords


Nitrogen heterocycles; Isosteres; Heterocyclization; Palladium-catalyzed couplings; Radical reactions

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