HETARYL-SUBSTITUTED BICYCLO[1.1.1]PENTANES

Authors

  • Oleksandr O. Grygorenko Enamine Ltd.; Taras Shevchenko National University of Kyiv
  • Serhii O. Kokhan Enamine Ltd.; Taras Shevchenko National University of Kyiv

DOI:

https://doi.org/10.1007/5352

Keywords:

Nitrogen heterocycles, Isosteres, Heterocyclization, Palladium-catalyzed couplings, Radical reactions

Abstract

Synthesis and properties of heterocycles bearing bicyclo[1.1.1]pentane moiety attached to the heterocyclic ring are summarized in this microreview. In particular, heterocyclizations with bicyclo[1.1.1]pentane derivatives, as well as reactions involving incorporation of the preexisting heterocyclic system into the bicyclo[1.1.1]pentane core are discussed.

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Published

2019-09-27

Issue

Vol. 55 No. 10 (2019)

Section

Heterocycles in Focus