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SYNTHESIS OF BENZO[c][1,7]NAPHTHYRIDINE DERIVATIVES

Антон Л. Шацаускас, Элина Р. Сайбулина, Юрий В. Гатилов, Анастасия С. Костюченко, Александр С. Фисюк
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Abstract


Reactivity of 2-methyl-6-phenylbenzo[c][1,7]naphthyridine in alkylation, oxidation, and electrophilic substitution reactions has been studied. The reaction of 2-methyl-6-phenylbenzo[c][1,7]naphthyridines with POCl3 yielded the previously unknown 4-chloro-2-methyl-6-phenylbenzo[c]-[1,7]naphthyridine. Its dehalogenation and substitution of halogen by nitrogen and sulfur nucleophiles were studied.

Keywords


benzo[c][1,7]naphthyridine; alkylation; electrophilic substitution; nucleophilic substitution; oxidation; reactivity.

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