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SYNTHESIS AND SOME CHEMICAL PROPERTIES OF 2-CYANO-4-PYRONE

Дмитрий Л. Обыденнов, Aлександра И. Суслова, Вячеслав Я. Сосновских
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Abstract


2-Cyano-4-pyrone obtained from comanic acid ethyl ester reacts with amines and hydrazines with the opening of the pyrone ring and substitution of the cyano group to form carbamoylated aminoenones (yields 62–87%) and pyrazolylacetic acid hydrazides. The reactions of 2-cyano-4-pyrone with hydroxylamine or sodium azide involve exclusively the cyano group, which makes it possible to obtain 2-heteroaryl-4-pyrones and 2-heteroaryl-4-hydroxypyridines.

Authors: Dmitrii L. Obydennov*, Aleksandra I. Suslova, Vyacheslav Ya. Sosnovskikh


Keywords


carbamoylated enaminones; 2-cyano-4-pyrones; 2-heteroaryl-4-hydroxypyridines; 2-heteroaryl-4-pyrones; 4-oxo-1,4-dihydropyridine-3-carboxamides; pyrazoles

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