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A PERSPECTIVE ON ENVIRONMENTALLY BENIGN PROTOCOLS OF THIAZOLE SYNTHESIS

Arnab Chowdhury, Sagarkumar Patel, Ayushi Sharma, Anwesha Das, Payal Meshram, Amit Shard
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Abstract


Thiazole has widespread importance in materials and medicines. Several reviews are reported which cover essential properties of thiazoles such as pharmacological activities, structure-activity relationship studies, and various synthetic routes. However, synthesis based on a greener approaches, particularly metal-free reactions, usage of mild, nontoxic, recyclable catalysts, eco-sustainable protocols, efficient solvents have not been exclusively reviewed. Current review emphasizes green synthetic approaches for substituted thiazoles that have been performed within the last decade.

Keywords


thiazole; biodegradable chemicals; catalyst-free synthesis; environment-friendly synthesis; green synthesis; solvent-free synthesis.

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