CYCLOPROPYLATION OF HETEROCYCLIC CORES USING CYCLOPROPYLBORONIC DERIVATIVES

Authors

  • Oleksandr O. Grygorenko Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine, www.enamine.net Taras Shevchenko National University of Kyiv, 60 Volodymyrska St., Kyiv 01601, Ukraine
  • Oleksandr V. Hryshchuk Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine, www.enamine.net Taras Shevchenko National University of Kyiv, 60 Volodymyrska St., Kyiv 01601, Ukraine

DOI:

https://doi.org/10.1007/5458

Keywords:

organoboron compounds, cyclopropane, coupling reactions, nitrogen-containing heterocycles

Abstract

Methods for cyclopropane ring incorporation into various heterocyclic cores using cyclopropylsubstituted organoboron compounds are surveyed. In particular, Suzuki–Miyaura and Chan–Lam reactions, recent coupling processes involving organotrifluoroborates, as well as C–H activation of
heterocyclic substrates are discussed.

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Published

2020-01-31

Issue

Vol. 56 No. 1 (2020)

Section

Heterocycles in Focus