REGIOSELECTIVITY OF (3+2) CYCLOADDITION OF AZOMETHINE YLIDES TO ACTIVATED OLEFINS IN THE SYNTHESIS OF SPIRO[OXINDOLE-3,2′-PYRROLIDINE] DERIVATIVES

Abstract

The effect of the structure of the starting compounds on the regioselectivity of the (3+2) cycloaddition of azomethine ylides to olefins activated by electron-withdrawing groups in the synthesis of spiro[oxindole-3,2′-pyrrolidine] derivatives is generalized and analyzed.