Open Access Open Access  Restricted Access Subscription Access

REACTION OF N-BENZYL AZOMETHINE YLIDE WITH ARYL ISOTHIOCYANATES: SYNTHESIS OF (Z)-N-ARYL-3-BENZYLTHIAZOLIDINE-5-IMINES

Евгений М. Буев, Анна П. Осинцева, Владимир С. Мошкин, Вячеслав Я. Сосновских
Cover Image

Abstract


The reaction of aryl isothiocyanates with nonstabilized azomethine ylides generated in situ by various methods was studied. It was established that the use of N-(methoxymethyl)-N-(trimethylsilylmethyl)benzylamine in the presence of trifluoroacetic acid in the role of a catalyst led to the formation of (Z)-N-aryl-3-benzylthiazolidin-5-imines in 22–47% yields.

Authors: Evgeny M. Buev*, Anna P. Osintseva, Vladimir S. Moshkin, Vyacheslav Ya. Sosnovskikh


Keywords


azomethine ylides; isothiocyanates; thiazolidines; [3+2] cycloaddition

Full Text: PDF (Russian) Supplementary File(s): Supporting information (947KB)


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv