

AN EFFICIENT METHOD FOR ACCESSING CARBOANNULATED AND FUNCTIONALIZED [1,2,3]TRIAZOLO[4,5-b]PYRIDINES

Abstract
4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes upon heating under reflux in acetic acid in the presence of pyrrolidine react with cycloalkanones, acetylacetone, 1,3-cyclohexanediones, and malononitrile resulting in annulation of the pyridine ring with the formation of new derivatives of [1,2,3]triazolo[4,5-b]pyridine.
Keywords
acetylacetone; 4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes; 4-(N-Boc-amino)-1,2,3-triazoles; cycloalkanones; 1,3-cyclohexanediones; malononitrile; [1,2,3]triazolo[4,5-b]pyridine derivatives; annulation.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv