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AN EFFICIENT METHOD FOR ACCESSING CARBOANNULATED AND FUNCTIONALIZED [1,2,3]TRIAZOLO[4,5-b]PYRIDINES

Наталия A. Сирота, Сергей B. Кемский, Андрей В. Больбут, Игорь И. Чернобаев, Михаил В. Вовк
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Abstract


4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes upon heating under reflux in acetic acid in the presence of pyrrolidine react with cycloalkanones, acetylacetone, 1,3-cyclohexanediones, and malononitrile resulting in annulation of the pyridine ring with the formation of new derivatives of [1,2,3]triazolo[4,5-b]pyridine.

 


Keywords


acetylacetone; 4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes; 4-(N-Boc-amino)-1,2,3-triazoles; cycloalkanones; 1,3-cyclohexanediones; malononitrile; [1,2,3]triazolo[4,5-b]pyridine derivatives; annulation.

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