AN EFFICIENT METHOD FOR ACCESSING CARBOANNULATED AND FUNCTIONALIZED [1,2,3]TRIAZOLO[4,5-<i>b</i>]PYRIDINES

Authors

  • Наталия A. Сирота National University ''Kyiv-Mohyla Academy'', 2 Hrygorija Skovorody St., Kiev 04655, Ukraine
  • Сергей B. Кемский Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine
  • Андрей В. Больбут Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine
  • Игорь И. Чернобаев Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine
  • Михаил В. Вовк Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine

DOI:

https://doi.org/10.1007/5653

Keywords:

acetylacetone, 4-(N-Boc-amino)-1, 2, 3-triazole-5-carbaldehydes, 3-triazoles, cycloalkanones, 1, 3-cyclohexanediones, malononitrile, [1, 3]triazolo[4, 5-b]pyridine derivatives, annulation.

Abstract

4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes upon heating under reflux in acetic acid in the presence of pyrrolidine react with cycloalkanones, acetylacetone, 1,3-cyclohexanediones, and malononitrile resulting in annulation of the pyridine ring with the formation of new derivatives of [1,2,3]triazolo[4,5-b]pyridine.

 

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Published

2020-09-17

Issue

Vol. 56 No. 8 (2020)

Section

Original Papers