SYNTHESIS OF CYCLIC D-(+)-CAMPHORIC ACID IMIDES AND STUDY OF THEIR ANTIVIRAL ACTIVITY

Vladimir V. Chernyshov; Olga I. Yarovaya; Roman Yu. Peshkov; Nariman F. Salakhutdinov

doi:10.1007/5678

SYNTHESIS OF CYCLIC D-(+)-CAMPHORIC ACID IMIDES AND STUDY OF THEIR ANTIVIRAL ACTIVITY

Vladimir V. Chernyshov, Olga I. Yarovaya, Roman Yu. Peshkov, Nariman F. Salakhutdinov

Abstract

Several D-(+)-camphoric acid imides, not previously described in the literature, were synthesized with good yields. The synthesis of previously known imides was improved. The cytotoxicity and antiviral activity of all synthesized imides were studied.

Keywords

D-(+)-camphoric acid; D-(+)-camphoric acid anhydride; imides; antiviral activity; cytotoxicity.

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv

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