CONSTRUCTION AND CHARACTERIZATION OF 3,7-DICHLORO-<i>N</i>-(2,6-DIETHYLPHENYL)-<i>N</i>-(2-PROPOXYETHYL)QUINOLONE-8-CARBOXAMIDE: A POTENTIAL NOVEL PESTICIDE COMPOUND

Authors

  • Xi-Le Deng Hunan Provincial Key Laboratory for Biology and Control of Weeds, Hunan Agricultural Biotechnology Research Institute, Hunan Academy of Agricultural Sciences, 2 Yuanda Road, Changsha 410125, China
  • Chun-Hui Zhu Institute of Plant Protection, Hunan Academy of Agricultural Science, 2 Yuanda Road, Changsha 410125, China
  • Xiao-Mao Zhou Hunan Provincial Key Laboratory for Biology and Control of Weeds, Hunan Agricultural Biotechnology Research Institute, Hunan Academy of Agricultural Sciences, 2 Yuanda Road, Changsha 410125, China
  • Lian-Yang Bai Hunan Provincial Key Laboratory for Biology and Control of Weeds, Hunan Agricultural Biotechnology Research Institute, Hunan Academy of Agricultural Sciences, 2 Yuanda Road, Changsha 410125, China

DOI:

https://doi.org/10.1007/5680

Keywords:

pretilachlor, quinclorac, active substructure splicing, fungicidal activity, herbicide activity.

Abstract

A novel compound, 3,7-dichloro-N-(2,6-diethylphenyl)-N-(2- propoxyethyl)quinoline-8-carboxamide was synthesized by splicing together a chloro-substituted quinoline moiety found in quinclorac (a selective herbicide) and a substituted amide moiety found in pretilachlor (another selective herbicide) using the active substructure splicing method. The chemical structure of this compound was characterized by 1H, 13C NMR, FTIR, high-resolution mass spectra and X-ray diffraction analysis. Pesticide potency (herbicidal and fungicidal activity) of this compound was evaluated. This compound displayed excellent control efficiency against Echinochloa crusgalli
and also showed good fungicidal in vitro activity against Phytophthora capsici, Phytophthora sojae, and Phytophthora infestans.

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Published

2021-01-26

Issue

Vol. 57 No. 1 (2021)

Section

Original Papers