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NOVEL SYNTHETIC APPROACH TO PYRROLO[1,2-b]CINNOLINES

Anastasia T. Plieva, Petrakis N. Chalikidi, Andrey V. Gutnov, Anatolij M. Turiev, Oleg P. Demidov, Nicolai A. Aksenov, Taimuraz T. Magkoev, Vladimir T. Abaev
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Abstract


Straightforward method for the synthesis of pyrrolo[1,2-b]cinnolines starting from 2-nitrobenzaldehydes and 2-methylfurans has been elaborated. The key steps of the process are oxidative furan ring opening with diazonium cation and intramolecular alkylation of azo group of the resulted cinnoline with secondary allyl alcohol.

Keywords


aza-heterocycles; cinnolines; pyrrolo[1,2-b]cinnolines; furan ring opening.

Full Text: PDF Supplementary File(s): Supporting information (2MB)


 

 

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