

PHOTOREGULATED MACROCYCLIC CELL-PENETRATING PEPTIDES

Abstract
Light-controlled cell-penetrating peptides are reviewed as emerging photopharmacology tools. Key discoveries made recently in this area demonstrated that photoregulation of the cell-penetrating ability is very efficient in structural contexts of (macro)heterocyclic peptidic molecules, containing azobenzene or diarylethene photoisomerizable moieties.
Keywords
macrocycles; cell-penetrating peptides; photoswitches; diarylethenes; azobenzenes; photopharmacology
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv