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PHOTOREGULATED MACROCYCLIC CELL-PENETRATING PEPTIDES

Igor V. Komarov, Iuliia V. Bakanovych
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Abstract


Light-controlled cell-penetrating peptides are reviewed as emerging photopharmacology tools. Key discoveries made recently in this area demonstrated that photoregulation of the cell-penetrating ability is very efficient in structural contexts of (macro)heterocyclic peptidic molecules, containing azobenzene or diarylethene photoisomerizable moieties.

Keywords


macrocycles; cell-penetrating peptides; photoswitches; diarylethenes; azobenzenes; photopharmacology

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