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2-YLIDENE-1,3-THIAZOLIDINES AND THEIR NONHYDROGENATED ANALOGS: METHODS OF SYNTHESIS AND CHEMICAL PROPERTIES

Мария Б. Литвинчук, Антон В. Бентя, Наталия Ю. Сливка, Михаил В. Вовк
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Abstract


The review summarizes and systematizes the literature data on the methods of synthesis and chemical properties of 2-ylidene-1,3-thiazolidines and 2-ylidene-2,3-dihydro-1,3-thiazoles. Two general approaches to their preparation have been identified: the construction of the 2-ylidene-1,3-thiazolidine ring from acyclic precursors in one synthetic process and the introduction of the 2-ylidene fragment into the 1,3-thiazolidine ring. The main chemical transformations of 2-ylidene-1,3-thiazolidines and 2-ylidene-2,3-dihydro-1,3-thiazoles, which include the reactions of selective functionalization and heterocyclization at the ylidene fragment and thiazolidine backbone, are considered. The bibliography of the review consists of 97 references published from 2000 to 2020.

Authors: Mariia B. Litvinchuk*, Anton V. Bentya, Nataliia Yu. Slyvka, Mikhailo V. Vovk


Keywords


2-ylidene-1,3-thiazolidines; 2-ylidene-2,3-dihydro-1,3-thiazoles; cyclocondensation; electrophilic cyclization; functionalization

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