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SYNTHESIS OF 1,8-NAPHTHYRIDINES: A RECENT UPDATE

Mahesh R. Kulkarni, Nitin D. Gaikwad
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Abstract


This microreview focuses on the recent achievements (2015–2019) toward the synthesis of 1,8-naphthyridines, which include multicomponent reactions, Friedländer approach using green strategy, hydroamination of terminal alkynes followed by Friedländer cyclization, metal-catalyzed synthesis, and ring expansion reaction of 3-substituted 1H-pyrrolo[2,3-b]pyridin-2(3H)-one.

Keywords


Eaton's reagent; 1,8-naphthyridine; synthesis

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv