Open Access Open Access  Restricted Access Subscription Access

SYNTHESIS AND BIOLOGICAL ACTIVITIES OF 4H-3,1-BENZOTHIAZIN-4-ONES

Lan Phuong Vu, Michael Gütschow
Cover Image

Abstract


4H-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4H-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.

Keywords


4H-3,1-benzothiazin-4-ones; enzyme inhibitors; receptors antagonists; ring closure

Full Text: PDF Supplementary File(s): None


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv