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SYNTHESIS OF α-SPIROCYCLIC PYRROLIDINES

Kostiantyn P. Melnykov, Sergey V. Ryabukhin
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Abstract


Different approaches and recent advances in methodologies for the synthesis of α-spirocyclic pyrrolidines are presented. The microreview covers the latest selected examples (2009–2019) on the synthesis of such compounds based on pyrrolidine ring construction. The advantages and features of the methods are discussed.

Keywords


pyrrolidines; spirocycles; heterocyclization

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