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SYNTHESIS OF NEW PYRIDO[4,3-e][1,2,4]TRIAZOLO[5,1-c][1,2,4]TRIAZIN-6(7H)-ONES

Мохаммад Н. Мавлуд, Михаил А. Потапов, Ирина В. Леденева, Олег А. Козадеров, Надежда В. Столповская, Хидмет С. Шихалиев, Андрей Ю. Потапов
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Abstract


Coupling of 3-substituted 1,2,4-triazole-5-diazonium salts with ethyl acetoacetate afforded 1,2,4-triazol-5-ylhydrazones, the reaction of
which with dimethylformamide dimethyl acetal leads to the formation of the corresponding readily separable 4-[2-(dimethylamino)vinyl][1,2,4]triazolo[5,1-c][1,2,4]triazine-3-carboxylates. New pyrido[4,3-e][1,2,4]triazolo[5,1-c][1,2,4]triazin-6(7H)-ones were synthesized by the condensation of the latter with primary amines.

Keywords


enamine; ethyl acetoacetate; dimethylformamide dimethyl acetal; hydrazone; pyrido[4,3-e][1,2,4]triazolo[5,1-c][1,2,4]triazine; 1,2,4- triazole-5-diazonium salt; [1,2,4]triazolo[5,1-c][1,2,4]triazine.

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