

MULTICOMPONENT SYNTHESIS OF NICOTINIC ACID DERIVATIVES

Abstract
The synthesis of previously unknown nitriles, esters, and an amide of 6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid has been developed. The structure of a number of the obtained derivatives was proved by X-ray structural analysis.
Keywords
6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid; СH acids, thiazolo[3,2-a]pyridines; alkylation; Michael reaction; multicomponent synthesis; X-ray structural analysis.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv