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MULTICOMPONENT SYNTHESIS OF NICOTINIC ACID DERIVATIVES

Иван В. Дяченко, Владимир Д. Дяченко, Павел В. Дороватовский, Виктор Н. Хрусталев, Валентин Г. Ненайденко
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Abstract


The synthesis of previously unknown nitriles, esters, and an amide of 6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid has been developed. The structure of a number of the obtained derivatives was proved by X-ray structural analysis.

Keywords


6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid; СH acids, thiazolo[3,2-a]pyridines; alkylation; Michael reaction; multicomponent synthesis; X-ray structural analysis.

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