

BIOLOGICALLY ACTIVE COMPOUNDS AND DRUGS IN THE TETRAZOLE SERIES

Abstract
The review summarizes the advances in medicinal chemistry of tetrazole biologically active compounds and drugs over the past 15 years. Most of the considered compounds are at present actively studied, are in various stages of clinical trials, or have recently been approved for use as pharmaceuticals.
Keywords
tetrazoles; bioisosterism; biological activity; drugs; medicinal chemistry.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv