SYNTHESIS AND PROPERTIES OF 5-ACETYL-3-CYANO-4-ISOBUTYL-6-METHYL-3,4-DIHYDROPYRIDINE-2(1H)-THIONE

Authors

  • C. Г. Кривоколыско T. G. Shevchenko Lugansk State Pedagogical Institute
  • B. Д. Дяченко T. G. Shevchenko Lugansk State Pedagogical Institute
  • B. П. Литвинов N. D. Zelinskii Institute of Organic Chemistry of the Russian Academy of Sciences

DOI:

https://doi.org/10.1007/593

Abstract

Condensation of isovaleric aldehyde with cyanothioacetamide and acetylacetone or its enamine produces 5-acetyl-3-cyano-4-isobutyl-6-methyl-3,4-dihydropyridine-2(1H)-thione, from which 5-acetyl-3-cyano-4-isobutyl-6-methylpyridine-2(1H)-thione and the corresponding substituted 2-alkylthio-1,4-dihydropyridines are prepared.

Authors: S. G. Krivokolysko, V. D. Dyachenko, and V. P. Litvinov.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (4), pp 455-458

http://link.springer.com/article/10.1007/BF02319334

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Published

2013-05-10

Issue

No. 4 (1999)

Section

Original Papers