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THE DIMROTH REARRANGEMENT IN THE SYNTHESIS OF CONDENSED PYRIMIDINES – STRUCTURAL ANALOGS OF ANTIVIRAL COMPOUNDS
Abstract
The review discusses the use of the Dimroth rearrangement in the synthesis of condensed pyrimidines which are key structural fragments of antiviral agents. The main attention is given to publications over the past 10 years. The bibliography includes 107 references.
Keywords
furo[2,3-d]pyrimidines; imidazo[1,2-a]pyrimidines; purines, pyrazolo[3,4-d]pyrimidines; pyrrolo[2,3-d]pyrimidines; quinazolin(on)es; thieno[2,3-d]pyrimidines; [1,2,4]triazolo[1,5-a]pyrimidines; [1,2,4]triazolo[1,5-c]pyrimidines; antiviral activity; Dimroth rearrangement.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv