UNSATURATED CARBOXYLIC ACIDS IN THE ONE-POT SYNTHESIS OF NOVEL DERIVATIVES OF 3,4-DIHYDRO-2<i>H</i>-THIOPYRAN
Authors
Екатерина А. Меркулова
Yaroslavl State Technical University,
88 Moskovsky Ave., Yaroslavl 150023, Russia
Алексей В. Колобов
Yaroslavl State Technical University,
88 Moskovsky Ave., Yaroslavl 150023, Russia
Константин Л. Овчинников
Yaroslavl State Technical University,
88 Moskovsky Ave., Yaroslavl 150023, Russia
Виктор Н. Хрусталев
RUDN University, 6 Miklukho-Maklaya St., Moscow 117198, Russia;
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
Валентин Г. Ненайденко
Lomonosov Moscow State University,
1, Build. 3 Leninskie Gory, Moscow 119991, Russia
The reactions of α,β-unsaturated ketones and Lawesson's reagent with maleic, itaconic, or 5-norbornene-2,3-dicarboxylic acid led to the corresponding 3,4-dihydro-2H-thiopyran anhydrides. As a result of the reaction of methacrylic acid, Lawesson's reagent, and chalcone, 4-methyl-1,8-diphenyl-2,6-dithiabicyclo[2.2.2]octan-3-one is formed. The selectivity of the acylation of amines using the synthesized anhydrides was studied.
