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BIOLOGICAL ACTIVITY AND SYNTHESIS OF 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID – BIOSYNTHETIC PRECURSOR OF MELANINS

Михаил А. Барабанов, Георгий С. Мартьянов, Александр В. Пестов
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Abstract


The microreview considers the biological activity and methods of obtaining natural melanin pigments and their biosynthetic precursor 5,6-dihydroxyindole-2-carboxylic acid. The key methods for the synthesis of 5,6-dihydroxyindole-2-carboxylic acid, published over the past 8 years (2012–
2020), are presented.

Keywords


Melanin, indolecarboxylic acid, cancer, antiviral drugs, arbidol, immunodeficiency, coronavirus

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