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2H-AZIRINES IN MEDICINAL CHEMISTRY

Павел А. Сахаров, Михаил С. Новиков, Николай В. Ростовский
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Abstract


The review presents an analysis of studies published in the period 1971–2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.

 


Keywords


2Н-azirines, bioconjugation, biological activity, cycloaddition, natural compounds.

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