

SELECTIVE SYNTHESIS OF A NOVEL GLYCOLURIL-BASED HYBRID COMPOUND WITH HIGH APPLICATION POTENTIAL

Abstract
Highly selective synthesis of a new antipyrine-substituted tetracycle was implemented on the basis of a modified Mannich reaction as a result of the condensation of glycoluril with 4-aminoantipyrine in formalin without the use of catalysts.
Keywords
4-aminoantipyrine; bicyclic bisureas; glycoluril; aminomethylation; aza-heterocyclization; condensation; Mannich reaction.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv