SELECTIVE SYNTHESIS OF A NOVEL GLYCOLURIL-BASED HYBRID COMPOUND WITH HIGH APPLICATION POTENTIAL

Authors

  • Елена А. Мамаева National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia
  • Анастасия В. Леппа National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia
  • Абдигали А. Бакибаев National Research Tomsk State University, 36 Lenina St., Tomsk 634050, Russia

DOI:

https://doi.org/10.1007/6179

Keywords:

4-aminoantipyrine, bicyclic bisureas, glycoluril, aminomethylation, aza-heterocyclization, condensation, Mannich reaction.

Abstract

Highly selective synthesis of a new antipyrine-substituted tetracycle was implemented on the basis of a modified Mannich reaction as a result of the condensation of glycoluril with 4-aminoantipyrine in formalin without the use of catalysts.

Author Biographies

Елена А. Мамаева, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia

Отделение химической инженерии Инженерной школы природных ресурсов ТПУ, доцент

Анастасия В. Леппа, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia

Отделение химической инженерии Инженерной школы природных ресурсов ТПУ, бакалавр

Абдигали А. Бакибаев, National Research Tomsk State University, 36 Lenina St., Tomsk 634050, Russia

Ведущий научный сотрудник ТГУ, профессор

Published

2021-06-19

Issue

Section

Short Communications