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SELECTIVE SYNTHESIS OF A NOVEL GLYCOLURIL-BASED HYBRID COMPOUND WITH HIGH APPLICATION POTENTIAL

Елена А. Мамаева, Анастасия В. Леппа, Абдигали А. Бакибаев
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Abstract


Highly selective synthesis of a new antipyrine-substituted tetracycle was implemented on the basis of a modified Mannich reaction as a result of the condensation of glycoluril with 4-aminoantipyrine in formalin without the use of catalysts.

Keywords


4-aminoantipyrine; bicyclic bisureas; glycoluril; aminomethylation; aza-heterocyclization; condensation; Mannich reaction.

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