

SYNTHESIS OF THE FIRST DITHIAAZA-17-CROWN-5 ETHERS CONTAINING PIPERIDIN-4-ONE SUBUNIT

Abstract
Dithiaaza-17-crown-5 ethers containing piperidin-4-one subunit and dithiacrown ether fragment were synthesized in one-pot Petrenko–Kritschenko reaction from 2,2'-[ethane-1,2-diylbis(oxyethane-2,1-diylsulfanediyl)]dibenzaldehyde, methyl ethyl ketone or dibenzyl ketone, and ammonium acetate. Molecular structure of dithiaaza-17-crown-5 ethers were confirmed by NMR, HRMS, and single crystal X-ray diffraction.
Keywords
dithiaaza-17-crown-5 ether; 2,2'-[ethane-1,2-diylbis(oxyethane-2,1-diylsulfanediyl)]dibenzaldehyde; domino reaction; Petrenko– Kritschenko reaction.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv