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SYNTHESIS OF THE FIRST DITHIAAZA-17-CROWN-5 ETHERS CONTAINING PIPERIDIN-4-ONE SUBUNIT

Thanh Van Tran Thi, Manh Linh Nguyen, Tien Dat Nguyen, The Duan Le, Hong Hieu Truong, Victor N. Khrustalev, Tuan Anh Le
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Abstract


Dithiaaza-17-crown-5 ethers containing piperidin-4-one subunit and dithiacrown ether fragment were synthesized in one-pot Petrenko–Kritschenko reaction from 2,2'-[ethane-1,2-diylbis(oxyethane-2,1-diylsulfanediyl)]dibenzaldehyde, methyl ethyl ketone or dibenzyl ketone, and ammonium acetate. Molecular structure of dithiaaza-17-crown-5 ethers were confirmed by NMR, HRMS, and single crystal X-ray diffraction.


Keywords


dithiaaza-17-crown-5 ether; 2,2'-[ethane-1,2-diylbis(oxyethane-2,1-diylsulfanediyl)]dibenzaldehyde; domino reaction; Petrenko– Kritschenko reaction.

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