REDUCTIVE ABILITY OF 1,4-DIHYDROPYRIDINE DERIVATIVES IN RELATION TO IONS OF TRIVALENT IRON

Abstract

3,5-Dicarbonyl derivatives of 2,6-dimethyl-1,4-dihydropyridine (1,4-DHP) can reduce Fe3+ to Fe2+ depending on the nature of the substituents at position 4 and in the 3,5-ester group. This ability is less pronounced for the 1,4-DHP derivatives investigated than for ascorbic acid, but among derivatives possessing antioxidant activity it is less than that of the known antioxidants ionol (BOT) and trolox.

Authors: D. Tirzite, G. Tirzitis, and D. Antipova.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (5), pp 592-594

http://link.springer.com/article/10.1007/BF02324644