

PREPARATION OF AN ADDUCT OF LEVOGLUCOSENONE AND RESORCINOL AND ITS in vitro ANTIPLATELET AND ANTICOAGULANT ACTIVITY

Abstract
A procedure for the preparation of an adduct of levoglucosenone and resorcinol was developed involving ultrasonic irradiation in the presence of K2CO3 and 18-crown-6 ether in toluene. In vitro anticoagulant and antiplatelet activity of the adduct was studied.
Keywords
Michael adducts; levoglucosenone; mixed ketal; resorcinol; antiplatelet activity; anticoagulant activity.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv