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PREPARATION OF AN ADDUCT OF LEVOGLUCOSENONE AND RESORCINOL AND ITS in vitro ANTIPLATELET AND ANTICOAGULANT ACTIVITY

Лилия Х. Файзуллина, Юлия А. Халилова, Фарид А. Валеев, Валентин Н. Павлов, Александр В. Самородов
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Abstract


A procedure for the preparation of an adduct of levoglucosenone and resorcinol was developed involving ultrasonic irradiation in the presence of K2CO3 and 18-crown-6 ether in toluene. In vitro anticoagulant and antiplatelet activity of the adduct was studied.

 


Keywords


Michael adducts; levoglucosenone; mixed ketal; resorcinol; antiplatelet activity; anticoagulant activity.

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