SYNTHESIS OF 2,3-DIHYDRO-1,4-BENZOXATHIINE DERIVATIVES

Abstract

2,3-Dihydro-1,4-benzoxathiine derivatives are important biologically active heterocyclic compounds. Approaches toward synthesis of 2,3-dihydro-1,4-benzoxathiine derivatives are summarized in this minireview, covering most important synthetic methods that might be gathered in six distinct categories: the intermolecular cyclizations of o-mercaptophenols, 2-mercaptoethanols, and their equivalents, cyclizations, cycloadditions, ring contractions and expansions, and reduction of 2,3-dihydro-1,4-benzoxathiine 4-oxides.