

REGIOSELECTIVE [3+2] CYCLOADDITION OF NITRILE OXIDES TO 1Н-PYRROLE-2,3-DIONES: SYNTHESIS OF SPIRO[PYRROLEDIOXAZOLES]

Abstract
1,3-Dipolar cycloaddition of 1H-pyrrole-2,3-diones to nitrile oxides generated in situ from N-hydroxybenzimidoyl chlorides by the action of triethylamine proceeds regioselectively with the formation of 1,4,2-dioxazoles spiro-condensed with the pyrrol-2-one fragment.
Keywords
1,4,2-dioxazoles; 1,3-dipoles; nitrile oxides; 1H-pyrrole-2,3-diones; 1,3-dipolar cycloaddition.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv