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SYNTHESIS, BIOLOGICAL ACTIVITY AND PHOTOPHYSICAL STUDIES OF ELLIPTICINE AND ITS DERIVATIVES: STATE OF THE ART
Abstract
The present review aims at surveying literature on the synthesis, biological and photophysical activities, especially anticancer properties, of tetracyclic natural compound ellipticine (5,11-dimethyl-6H-pyrido[4,3-b]carbazole) since its first isolation and synthesis in 1959.
Keywords
ellipticine; Apocynaceae family; biological activity; cytotoxic activity; DNA intercalation; photophysics; reverse micelles
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv