

SYNTHESIS OF 5,11-DIALKYL-5,6,11,12-TETRAHYDRO-6,12-EPOXYDIBENZO[b,f][1,5]DIAZOCINES FROM 2-ALKYLAMINOBENZALDEHYDES

Abstract
A simple methodology was developed for the synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines by treatment of the respective 2-alkylaminobenzaldehydes with hydrogen chloride solution in dioxane at room temperature.
Keywords
2-alkylaminobenzaldehydes; tetrahydrodiazocines; Tröger's base; acidic catalysis.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv