СИНТЕЗ 5,11-ДИАЛКИЛ-5,6,11,12-ТЕТРАГИДРО-6,12-ЭПОКСИДИБЕНЗО[<i>b</i>,<i>f</i>][1,5]ДИАЗОЦИНОВ ИЗ 2-АЛКИЛАМИНОБЕНЗАЛЬДЕГИДОВ

Дмитрий С. Иванов; Эльвира Р. Зайцева; Александр Ю. Смирнов; Надежда С. Балеева; Михаил С. Баранов

doi:10.1007/6627

Authors

Дмитрий С. Иванов Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997, GSP-7; Russia
Эльвира Р. Зайцева Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997, GSP-7; Russia
Александр Ю. Смирнов Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997, GSP-7; Russia Pirogov Russian National Research Medical University, Ministry of Health and Social Development of the Russian Federation, 1 Ostrovityanova St., Moscow 117997, Russia
Надежда С. Балеева Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997, GSP-7; Russia Pirogov Russian National Research Medical University, Ministry of Health and Social Development of the Russian Federation, 1 Ostrovityanova St., Moscow 117997, Russia
Михаил С. Баранов Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997, GSP-7; Russia Pirogov Russian National Research Medical University, Ministry of Health and Social Development of the Russian Federation, 1 Ostrovityanova St., Moscow 117997, Russia

DOI:

https://doi.org/10.1007/6627

Keywords:

2-alkylaminobenzaldehydes, tetrahydrodiazocines, Tröger's base, acidic catalysis.

Abstract

A simple methodology was developed for the synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines by treatment of the respective 2-alkylaminobenzaldehydes with hydrogen chloride solution in dioxane at room temperature.