SYNTHESIS OF [1,3]BENZOXAZINO[2,3-<i>k</i>]- AND [2,4]BENZODIAZEPINO[3,2-<i>k</i>]CARBAZOLE DERIVATIVES

Abstract

Alkylation of 4a-methyl-, 4a,6-dimethyl- and 6-bromo-4a-methyl-2,3,4,4a-tetrahydro-1H-carbazoles using 2-chloromethyl-4-nitrophenol gives [1,3]benzoxazino[2,3-k]carbazoles. Derivatives of [2,4]benzodiazepino-[3,2-k]carbazole have been synthesized by alkylation of the indicated carbazolenines using 2-bromomethylbenzonitrile followed by hydrolysis of the nitrile group of the 9-(2-cyanobenzyl)-carbazolium salts obtained to amide.

Authors: A. Shachkus, S. Krikshtolaitite, and V. Martinaitis.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (6), pp 729-732

http://link.springer.com/article/10.1007/BF02251634