о-AMINOPYRIMIDINE ALDEHYDES AND KETONES: SYNTHESIS AND USE AS PRECURSORS TO FUSED PYRIMIDINES

Abstract

The review summarizes literature data on the methods of synthesis of o-aminopyrimidine aldehydes and o-aminopyrimidine ketones and their application for the construction of fused pyrimidines, in particular pyrido[2,3-d]pyrimidines, pyrimido[4,5-d]pyrimidines, pyrazolo[3,4-d]pyrimidines, quinazolines, pyrimido[4,5,6-de]quinazolines, thieno[2,3-d]pyrimidines, pyrrolo[2,3-d]pyrimidines, cyclopenta[d]-
pyrimidines, pyrimido[4,5-b]azepines, and pyrimido[4,5-b]quinolines.

Authors: Alexander V. Komkov, Anna А. Sukhanova, Leonid G. Menchikov, Igor V. Zavarzin*