

SYNTHESIS OF SPIRO[IMIDAZOLE-4,3'-THIOCHROMAN]ONES FROM [2-(BENZYLSULFANYL)BENZYLIDENE]IMIDAZOLONES

Abstract
A methodology was developed for the synthesis of phenylspiro[imidazole-4,3'-thiochroman]ones by treatment of [2-(benzylsulfanyl)benzylidene]imidazolones with titanium tetrachloride. The reaction proceeded according to [1,5]-hydride shift mechanism followed by thiochromane ring closure.
Authors: Elvira R. Zaitseva, Anatolii I. Sokolov, Andrey A. Mikhaylov, Nadezhda S. Baleeva, Mikhail S. Baranov, Alexander Yu. Smirnov*
Keywords
benzylideneimidazolones; thiochromanes; titanium tetrachloride; C–H activation; [1,5]-hydride shift
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv