TETRAHYDROAZEPINES WITH AN ANNULATED FIVE-MEMBERED HETEROAROMATIC RING

Abstract

The review summarizes and analyzes the literature data on the synthetic design of promising biologically active hydrogenated furo-, thieno-, pyrrolo-, and azoloazepine systems. The information is systematized according to the principle of prevalence and significance of the employed synthetic methods: annulation of an azepine ring to a five-membered heteroaromatic ring, annulation of a five-membered heteroaromatic ring to an azepine ring, ring expansion reactions of hetaro-annulated cyclohexanones and piperidines. The bibliography of the review contains 94 sources published in 2000–2022.

Authors: Ivanna Yu. Danyliuk*, Mykhailo V. Vovk