METHYL 3-ARYL(PYRIDYL)-5-OXOPYRROLIDINE-2-CARBOXYLATES: SYNTHESIS AND STRUCTURE

Authors

  • Наталья В. Городничева Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia
  • Ольга С. Васильева Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia
  • Евгений С. Остроглядов Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia
  • Руслан И. Байчурин Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia
  • Игорь А. Литвинов A. E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center, Russian Academy of Sciences, 8 Arbuzova St., Kazan 420088, Russia
  • Сергей В. Макаренко Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia

DOI:

https://doi.org/10.1007/6921

Keywords:

lactams, 5-oxopyrrolidine-2-carboxylates, 2-pyrrolidone, pyroglutamic acid esters.

Abstract

A convenient diastereoselective method for the preparation of methyl (2R*,3R*)-3-aryl(pyridyl)-5-oxopyrrolidine-2-carboxylates was developed on the basis of the neutralization reaction of diastereohomogeneous dimethyl (2R*,3R*)-3-aryl(pyridyl)glutamate hydrochlorides.

 

Author Biography

Наталья В. Городничева, Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia

Д.х.н., доцент.

Факультет химии РГПУ им. А.И. Герцена - декан

Кафедра органической химии РГПУ им. А.И.Герцена - заведующий кафедрой.

ЦКП при факультете химии РГПУ им. А.И.Герцена - директор

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Published

2023-02-21

Issue

Vol. 59 No. 1/2 (2023)

Section

Original Papers