Open Access Open Access  Restricted Access Subscription Access

METHYL 3-ARYL(PYRIDYL)-5-OXOPYRROLIDINE-2-CARBOXYLATES: SYNTHESIS AND STRUCTURE

Наталья В. Городничева, Ольга С. Васильева, Евгений С. Остроглядов, Руслан И. Байчурин, Игорь А. Литвинов, Сергей В. Макаренко
Cover Image

Abstract


A convenient diastereoselective method for the preparation of methyl (2R*,3R*)-3-aryl(pyridyl)-5-oxopyrrolidine-2-carboxylates was developed on the basis of the neutralization reaction of diastereohomogeneous dimethyl (2R*,3R*)-3-aryl(pyridyl)glutamate hydrochlorides.

 


Keywords


lactams; 5-oxopyrrolidine-2-carboxylates; 2-pyrrolidone; pyroglutamic acid esters.

Full Text: PDF (Russian) Supplementary File(s): Supplementary information (1MB)


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv