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METHODS FOR THE PREPARATION OF 2-NITROBENZOFURANS

Дмитрий В. Осипов, Дарья А. Ращепкина, Павел Е. Красников, Виталий А. Осянин
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Abstract


The review summarizes the existing methods for the synthesis of 2-nitrobenzofurans and their polycondensed derivatives, which present valuable substrates for effecting dearomatization of the furan ring. Electrophilic nitration of 2-unsubstituted benzofurans, ipso substitution, condensation of salicylic aldehydes with bromonitromethane, and oxidation of 2-(2-nitroethyl)phenols have received the most attention.

 


Keywords


bromonitromethane; chloronitrostyrenes; 2-nitrobenzofurans; 2-(2-nitroethyl)phenols; o-quinone methides; salicylic aldehydes; dearomatization; nitration; ipso substitution.

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